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Nereus Pharmaceuticals is a pioneer in the use of marine microbial sources for the discovery and follow-on development of new therapeutics for cancer and inflammatory and infectious diseases. Nereus Pharmaceuticals has a clinical pipeline of two potentially best-in-class small molecule oncology drugs in clinical trials. The pre-clinical pipeline consists of several new chemical entities (NCEs) that are modulators of IKK activity for the treatment of cancer and/or inflammatory diseases and two NCE leads with novel pharmacophores that are broad spectrum antibiotics for infectious disease therapy.