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Metaphore Pharmaceuticals, Inc. discovers and develops drugs for the treatment of diseases associated with free radical damage and inflammation. The company leverages its expertise in chemistry and biology to discover and develop small molecule compounds that mimic the activity of human enzymes. Metaphore's lead compounds mimic the function of superoxide dismutases (SODs), beneficial enzymes that serve an important protective role in the body by removing superoxide, a toxic free radical that can damage cells and tissues. These product candidates, two of which are in ongoing human clinical trials in the U.S., have broad therapeutic potential across a variety of diseases. Metaphore currently focuses its clinical development efforts in pain, rheumatoid arthritis and other inflammatory disorders. The company is headquartered in St. Louis, MO.