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HUMAN GENE THERAPY publishes scientific papers on original investigations into the transfer and expression of genes in mammals, including man. Improvements in vector development, delivery systems, and animal models are covered. Ethical/legal/regulatory papers relating directly to the area of gene transfer into humans are welcome. In addition, the Journal will publish Abstracts and Commentaries, Point/Counterpoint, and News and Comments, including ongoing Clinical Protocols, Regulations, Meetings, Industrial News, Patents, Publication Announcements, and Book Reviews.