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Agave BioSystems is a biotechnology-based small business founded in 1998 with administrative headquarters and engineering facilities in Austin, Texas and laboratories in Ithaca, New York. Agave BioSystems harnesses the extreme specificity and sensitivity of biological systems to build unique and useful nanoscale engineered devices and systems. Through our expertise in micro and nanofabrication techniques, much of the work centers on the miniaturization of lab-scale diagnostic and analytical instrumentation. Agave BioSystems is also engaged in a number of research projects where biological components for sensor systems are being tailored to complement ongoing work in the area of nanofabrication. Several of these sensors are being developed to combat biowarfare and bioterrorists agents, but will have broad application in the food, environmental and medical industries. Principal funding for our research and development activities is provided by a number of research contracts from agencies including the Department of Defense, the National Institutes of Health, the Environmental Protection Agency, and NASA. Agave BioSystems enjoys a close collaborative relationship with Cornell University and many of its research groups. Agave BioSystems has also established a highly sophisticated capability with its facilities in Ithaca, NY, Austin, TX and through business relationships with the New York State Center for Advanced Technology in Biotechnology, the Alliance for NanoMedical Technologies, and the Cornell Nanofabrication Facility. By these means, Agave BioSystems has access to a wide range of microfabrication, molecular biology, and biochemistry materials, equipment and facilities.