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City of Hope Orange County Lennar Foundation Cancer Center provides Irvine and surrounding communities with comprehensive care and innovative cancer treatments. Located close to where the 5 and 405 freeways meet, our expansive facility is patient-focused, offering highly specialized cancer care, clinical trials, precision medicine, and early detection and prevention programs. City of Hope cares for patients from prevention through survivorship by pairing our expertise in hematology, surgical and medical oncology, diagnostic radiology and more, with world-class technologies and services. Whether you have been recently diagnosed or want a second opinion, we offer expertise that comes from working with cancer patients every day.