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Applied Genomics is developing novel tools useful for the detection and classification of human cancer. We are accomplishing this by having developed a process whereby complex gene expression data is used to target antibody production and generate datasets of protein expression across thousands of tumor tissues. AGI has used these reagents and datasets to reveal a novel approach towards classification of cancer with great potential to account for the clinical variation among patients that clinicians have observed for decades. Applied Genomics initially began from a collaboration between Stanford University and Research Genetics located in Huntsville, AL (later acquired by Invitrogen, Inc.). AGI was founded in 2000 by Robert Seitz, CEO of AGI and previous founder and Director of the Antibody Department at Research Genetics, and Douglas T. Ross, MD, PhD, Chief Scientific Officer of AGI and former postdoctoral fellow in Patrick Brown's laboratory at Stanford University. The company has two facilities: corporate headquarters in Huntsville, AL where the antibodies are produced and a research facility in Burlingame, CA.