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The Journal of Lipid Research (JLR) focuses on the science of lipids in health and disease. The Journal emphasizes the regulation and mechanism of lipid function and metabolism, the genetic regulation of lipid metabolism, and the clinical and nutritional implications including patient-oriented research. The JLR aims to be on the forefront of the emerging areas of genomics, proteomics, and lipidomics. The JLR covers biochemistry, cell biology, molecular biology, structural biology, genetics, genomics, immunology, metabolism, nutrition and clinical science as they relate to lipids. The following are representative areas covered in the Journal: Adipose tissue metabolism Animal models of lipid abnormalities Antioxidants and lipid peroxidation Apolipoproteins, lipid transport and metabolism Atherogenesis Bile acids and bile acid metabolism Biophysics Brain lipids Cell signaling Cholesterol synthesis and trafficking Clinical studies elucidating lipid dysfunction Dietary lipids and disease prevention Eicosanoids Fatty acid binding proteins and metabolism Genomics of lipids Inborn errors in lipid metabolism Lipases in lipid processing Lipid enzymes Lipidomics Lipid micelle structure and organization Lipid transfer proteins Lipoproteins Membrane lipids and structure Model systems Modified lipoproteins Neutral lipids Oxidized LDL Oxysterols and sterol metabolism Phospholipids and phospholipases Protein-lipid interactions Receptors for lipids Sphingolipids JLR publishes original articles, including methods papers and short communications, as well as reviews. Articles describing patient-oriented research are also encouraged. Because JLR has worldwide distribution, contributions are encouraged from investigators in all countries, but articles must be submitted in clear and concise English. When submitting your manuscript to JLR, please see the Instructions to Authors.